Aicar(Acadesine)

Product Name:Aicar(Acadesine)

Synonyms:ACADESINE;AICAR;AICA-RIBOSIDE;AMPK;1-Deoxy-1-[(4-carbamoyl-5-amino-1H-imidazole)-1-yl]-β-D-ribofuranose;1-β-D-Ribofuranosyl-5-amino-1H-imidazole-4-carboxamide;5-Amino-1-β-D-ribofuranosyl-1H-imidazole-4-carboxamide;AICA-β-D-Riboside

CAS:2627-69-2

MF:C9H14N4O5

MW:258.23

EINECS:220-097-5

Product Categories:ARASINE;Cardiovascular APIs;PI3K/Akt/mTOR;PI3K;Bases & Related Reagents;Carbohydrates & Derivatives;Nucleotides;Protein Kinase;Akt;mTOR

Mol File:2627-69-2.mol

Melting point:214-215 °C

storage temp:−20°C Cool Dried Storage

solubility H2O:>10 mg/mL

Water Solubility:Soluble in DMSO at 2mg/ml. Soluble in water or ethanol at less than 1mg/ml

EPA Substance Registry System 1H-Imidazole-4-carboxamide, 5-amino-1-.beta.-D-ribofuranosyl- (2627-69-2)

HS Code:29349990

Chemical Properties:Solid

Place of Origin:China

Type:Blood System Agents

Grade Standard:Medicine Grade

Usage:Animal Pharmaceuticals, Animal Pharmaceuticals

Purity:99%

Inventory status:in stock

Sample:Available

Shelf life:2 Years Properly Stored

Appearance:White Powder

MOQ:0.1kg

Packaging Details:1-5 kg with zip-lock plastic bag inside,Aluminum foil bag outside.finally with waterproof bag. 6-15 kg with plastic bag inside,Aluminum foil bag outside,finally with carton box. More than 16 kg with plastic bag inside,fiber drum outside according to the extract quantity.

Application:AICAR is being clinically used to treat and protect against cardiac ischemic injury. If left untreated, it may lead to a myocardial infarct. Cardiac Ischemia is caused by insufficient blood flow and oxygen to the myocardium .The drug was first used in the 1980’s as a method to preserve blood flow to the heart during surgery. Currently,the drug has also been shown as a potential treatment for diabetes by increasing the metabolic activity of tissues by changing the physical composition of muscle.

(1) Applied in phamaceutical field, it is used as phamaceutical raw material to treat injuries from fall, infectious hepatitis and epidemic cerebrospinal meningitis. 

(2) Applied in healthcare field, it is used in the health products to nourish brain, protect liver and improve sleep quality.

(3) Applied in comestics, it is used to promote skin metabolism and make skin more tender and firm.

Product descrition:AICAR is a cell permeable activator of AMP-activated protein kinase(AMPK),a metabolic master regulator that is activated in times of reduced energyavailability(high cellular AMP:ATP ratios) and serves to inhibit anabolic processes. In vivo, pharmacologic activation of AMPK with AICAR mimics exercise and triggers insulins-independent glucose uptake by skeletal muscle.  

Cell-permeable, allosteric activator of AMP-activated protein kinase (AMPK). Augments proliferation, differentiation and mineralization of osteoblastic MC3T3-EI cells and attenuates psychosine-induced expression of proinflammatory cytokines and iNOS in astrocytes. Promotes osteogenic differentiation of hAMSCs and BM-MSCsin vitro.

Biological Activity:Cell-permeable, allosteric activator of AMP-activated protein kinase (AMPK). Augments proliferation, differentiation and mineralization of osteoblastic MC3T3-EI cells and attenuates psychosine-induced expression of proinflammatory cytokines and iNOS in astrocytes.

Payment Terms:Bank Transfer T/T,Western Union or Money Gram,Paypal

Delivery time:within 3 days after payment, 7-12 days to arrive.

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Our advantages:

High quality 

1.Competitive price

2.Fast Delivery Within 3 days

3.Professional factory