Raw Material and Intermediate

3-[[2-[[(4-carbamimidoylphenyl) amino]methyl]-1-methyl-benzoimidazole-5-carbonyl]-pyridin-2-yl-amino]propanoic acid

Product Name:3-[[2-[[(4-carbamimidoylphenyl) amino]methyl]-1-methyl-benzoimidazole-5-carbonyl]-pyridin-2-yl-amino]propanoic acid
Synonyms:Dabigatran;β-Alanine,N-[[2-[[[4-(aMinoiMinoMethyl)phenyl]aMino]Methyl]-1-Methyl-1H-benziMidazol-5-yl]carbonyl]-N-2-pyridinyl-;3-(2-((4-carbamimidoylphenylamino)methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoic acid;3-[[2-[(4-carbamimidoylanilino)methyl]-1-methylbenzimidazole-5-carbonyl]-pyridin-2-ylamino]propanoic acid Dabigatran (BIBR 953);Dabigatran Impurity b;Dabigatran (Acid);3-[[2-[(4-carbamimidoylanilino)methyl]-1-methylbenzimidazole-5-carbonyl]-pyridin-2-ylamino]propanoic;Dabigatran(BIB-953;3-[[2-[[(4-carbaMiMidoylphenyl)aMino]Methyl]-1-Met
Dabigatran (BIBR 953);3-[[2-[(4-carbamimidoylanilino)methyl]-1-methylbenzimidazole-5-carbonyl]-pyridin-2-ylamino]propanoic acid;UNII-I0VM4M70GC;BIBR 953,Dabigatran,BIBR953;Dabigatran;
BIBR-953;BIBR 953ZW;BIBR 953 (Dabigatran,Pradaxa);
Product Categories:Other APIs;Inhibitors;benzimidazol;Dabigatran impurity;Aromatics;Inhibitor;Intermediates & Fine Chemicals;Nucleotides;Pharmaceuticals;Bases & Related Reagents;Heterocycles
CAS:211914-51-1
MF:C25H25N7O3
Molecular Weight:471.51100
PSA:150.22000
LogP:3.85900
Density:1.38 g/cm3
Boiling Point:797.1ºC at 760 mmHg
Melting Point:268-272ºC
Flash Point:435.9ºC
Refractive Index:1.694
Vapor Pressure:8.45E-27mmHg at 25°C
Purity:99%min
Grade:Medical GRADE
Packaging Details:Foil bag/Drum/As your requirement  
Package:500G;1KG;5KG;25KG
Mol File:211914-51-1.mol
storage temp:Refrigerator, Under Inert Atmosphere
Chemical Properties:Tan Solid
Uses:BIBR 953 (Dabigatran, Pradaxa) is potent nonpeptide thrombin inhibitor with an IC50 of 9.3 Nm 
Nonpeptide, direct thrombin inhibitor. Antithrombotic.
Definition ChEBI: An aromatic amide obtained by formal condensation of the carboxy group of 2-{[(4-carbamimidoylphenyl)amino]methyl}-1-methyl-1H-benzimidazole-5-carboxylic acid with the secondary amoino group of N-pyridin-2-yl-b ta-alanine. The active metabolite of the prodrug dabigatran etexilate, it acts as an anticoagulant which is used for the prevention of stroke and systemic embolism.
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