3-[[2-[[(4-carbamimidoylphenyl) amino]methyl]-1-methyl-benzoimidazole-5-carbonyl]-pyridin-2-yl-amino]propanoic acid

Product Name:3-[[2-[[(4-carbamimidoylphenyl) amino]methyl]-1-methyl-benzoimidazole-5-carbonyl]-pyridin-2-yl-amino]propanoic acid
Synonyms:Dabigatran;β-Alanine,N-[[2-[[[4-(aMinoiMinoMethyl)phenyl]aMino]Methyl]-1-Methyl-1H-benziMidazol-5-yl]carbonyl]-N-2-pyridinyl-;3-(2-((4-carbamimidoylphenylamino)methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoic acid;3-[[2-[(4-carbamimidoylanilino)methyl]-1-methylbenzimidazole-5-carbonyl]-pyridin-2-ylamino]propanoic acid Dabigatran (BIBR 953);Dabigatran Impurity b;Dabigatran (Acid);3-[[2-[(4-carbamimidoylanilino)methyl]-1-methylbenzimidazole-5-carbonyl]-pyridin-2-ylamino]propanoic;Dabigatran(BIB-953;211914-51-1
CAS:211914-51-1
MF:C25H25N7O3
Product Categories:Other APIs;Inhibitors;benzimidazol;Dabigatran impurity;Aromatics;Inhibitor;Intermediates & Fine Chemicals;Nucleotides;Pharmaceuticals;Bases & Related Reagents;Heterocycles
Mol File:211914-51-1.mol
Melting point:268-272°C
storage temp:Refrigerator, Under Inert Atmosphere
Package:100g,500g,1kg,5kg,10kg
Uses:BIBR 953 (Dabigatran, Pradaxa) is potent nonpeptide thrombin inhibitor with an IC50 of 9.3 nM Nonpeptide, direct thrombin inhibitor. Antithrombotic.
Definition ChEBI:An aromatic amide obtained by formal condensation of the carboxy group of 2-{[(4-carbamimidoylphenyl)amino]methyl}-1-methyl-1H-benzimidazole-5-carboxylic acid with the secondary amoino group of N-pyridin-2-yl-b ta-alanine. The active metabolite of the prodrug dabigatran etexilate, it acts as an anticoagulant which is used for the prevention of stroke and systemic embolism.