API and Intermediate

GS-7340 (fuMarate)

Product Name:N-[(S)-[[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl] phenoxyphosphinyl]-L-llanine 1-methylethyl ester (2E)-2-butenedioate (1:1)
Chinese Name: GS 7340 富马酸盐
Synonyms:GS-7340 (fuMarate);L-Alanine, N-[(S)-[[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]phenoxyphosphinyl]-, 1-methylethyl ester, (2E)-2-butenedioate (1:1);tenofovir alafenamide fumarate (TAF);N-[(S)-[[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]phenoxyphosphinyl]-L-llanine 1-methylethyl ester (2E)-2-butenedioate (1:1);Tenofovir alafenamide fumarate (1:1 salt);Tenofovir alafenamide : fumarate = 1:1) ;vemlidy; TAF;GS-7340 fumarate;Tenofovir alafenamide fumarate, 1:1;
CAS:379270-38-9
MF:C21H29N6O5P.C4H4O4 
Molecular Weight:592.53800
PSA:227.89000
LogP:3.65680
Place of Origin:China
Type:Anesthetic Agents, Antibiotic and Antimicrobial Agents, Pharmaceutical Intermediates
Grade Standard:Medicine Grade
Usage:Animal Pharmaceuticals
Appearance:White
Purity:99%
Grade:Pharmaceutical Grade
Certificate:ISO/ FDA
COA:Avalibale
Shelf life:2 Years
Storage:Cold Dry Place
Packaging Details:Tenofovir Alafenamide Fumarate packing 1kg/ bag or 25kg/ drum 
according to customers requirement ,different package is available
Package:100g,500g,1KG,10KG,100KG
Description:Tenofovir alafenamide, also known as TAF and GS-7340, is a nucleotide reverse transcriptase inhibitor (NRTIs) and a novel prodrug of tenofovir. By blocking reverse transcriptase, TAF prevent HIV from multiplying and can reduce the amount of HIV in the body. Tenofovir alafenamide is a prodrug, which means that it is an inactive drug. In the body, tenofovir alafenamide is converted to tenofovir diphosphate (TFV-DP). Tenofovir alafenamide fumarate was approved in November 2015 for treatment of HIV-1.
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