Teneligliptin

Product Name:Teneligliptin
Synonyms:API (Teneligliptin free base);teneligliptin;[(2S,4S)-4-[4-(5-methyl-2-phenylpyrazol-3-yl)piperazin-1-yl]pyrrolidin-2-yl]-(1,3-thiazolidin-3-yl)methanone;3-[[(2S,4S)-4-[4-(3-Methyl-1-phenyl-1H-pyrazol-5-yl)-1-piperazinyl]-2-pyrrolidinyl]carbonyl]thiazolidine;Methanone,[(2S,4S)-4-[4-(3-Methyl-1-phenyl-1H-pyrazol-5-yl)-1-piperazinyl]-2-pyrrolidinyl]-3-thiazolidinyl-;Teneligptin WS; CS-0882;UNII-28ZHI4CF9C;teneligliptin;
CAS:760937-92-6
MF:C22H30N6OS
MW:426.58
Product Categories:Pharmaceutical Raw Materials,Active Pharmaceutical Ingredients,Bulk Drugs,Fine Chemicals.
Place of Origin:China
Type:Urinary System Agents
Grade Standard:Medicine Grade
Appearance:Teneligliptin powder
Mol File:760937-92-6.mol
Density:1.38
PSA:81.94000
LogP:1.83570
Purity:99% Teneligliptin
COA:Available
MSDS:Available
Inventory status:check with us before place order
Packaging Details
1g,5g,10g,50g,100g/bottle, 1kg/tin for trial order or specific packing required by customer 
25kg/drum, 40*50*40cm for commercial order quantity 
Package:100g,500g,1KG,10KG,100KG
Packaging:
1g,5g,10g,50g,100g/bottle.
1kg/tin for trial order.
25kg/drum for commercial quantity.
Specific packing required by customer.
Storage:Teneligliptin should be stored in a well-closed container at low temperature, keep away from moisture, heat and light.
Shelf life:2 years when properly stored
Note:Teneligliptin for R&D use only.
Delivery and Payment terms:
After your payment, we will send product within 3-5 days, our after-sales staff will give you full details of the delivery, also they will be at your service after you receive and test the goods
Description:Teneligliptin was approved in September 2012 in Japan for the treatment of patients with Type 2 diabetes mellitus (T2DM). Teneligliptin is a member of the dipeptidyl peptidase 4 (DPP-4) inhibitor class of antidiabetes agents. DPP-4 is an enzyme that degrades GLP-1, a 30-amino acid peptide that is secreted in response to food intake. GLP-1 stimulates insulin secretion and inhibits glucagon secretion, which leads to lower levels of plasma glucose. Teneligliptin is one of a growing numbers of DPP-4 inhibitors to be approved worldwide. The discovery of teneligliptin was guided by structure-based design, with a key element being binding of the phenyl group in the S2 pocket, which not only increases potency for DPP-4, but also improves selectivity versus DPP-8 and DPP- 9. Teneligliptin is a potent inhibitor of DPP-4 in the enzyme inhibition assay (IC50=0.37 nM).
Usage:Animal Pharmaceuticals, pharmaceutical raw materials
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