API and Intermediate

Formoterol

Product Name:Formoterol
Synonyms:rel-N-(2-Hydroxy-5-((R)-1-hydroxy-2-(((R)-1-(4-Methoxyphenyl)propan-2-yl)aMino)ethyl)phenyl)forMaMide;N-(2-Hydroxy-5-((R)-1-hydroxy-2-(((R)-1-(4-methoxyphenyl)propan-2-yl)amino)ethyl)phenyl)formamide;1-nitrotridec-1-ene;n-[2-hydroxy-5-[1-hydroxy-2-[1-(4-methoxyphenyl)propan-2-ylamino]ethyl]phenyl]formamide;FORMOTEROL TARTRATE;FORMOTEROL;FORMOTEROL TARTARATE;FormoterolBase;
CAS:73573-87-2
MF:C19H24N2O4
MW:344.4
HS Code:2924299090
Place of Origin:China
Type:Respiratory System Agents
Product Categories:Other APIs;Inhibitors;(intermediates of formoterol )
Grade Standard:Medicine Grade
Mol File:73573-87-2.mol
solubility DMSO:20 mg/mL, soluble
Appearance & Physical State:off-white solid
Color:White or off white crystalline powder
Stability Stable:Incompatible with strong oxidizing agents.
PSA:90.82000
LogP:3.32310
Density:1.233 g/cm3
Boiling Point:603.2ºCat 760 mmHg
Flash Point:318.6ºC
Refractive Index:1.616
heavy metal:20ppm max
Water:≤0.5%
Purity:99%
Packaging Details
100g/bag with foil bag;1kg/bag with foil bag
Our packages of product: 100g/bag with foil bag;1kg/bag with foil bag
Package:500G;1KG;5KG;25KG
Usage:Animal Pharmaceuticals
Uses Labeled Formoterol, intended for use as an internal standard for the quantification of Formoterol by GC- or LC-mass spectrometry.
Definition ChEBI:A phenylethanoloamine having 4-hydroxy and 3-formamido substituents on the phenyl ring and an N-(4-methoxyphenyl)propan-2-yl substituent.
General Description Formoterol (Foradil) isalso a lipophilic (log P= 1.6) and long-acting β2-agonist. Ithas 3'-formylamino ( β-directing) and 4 OH groups on onephenyl ring and a lipophilic -directing N-isopropyl-pmethoxyphenylgroup on the nitrogen atom. Its long DOA(12 hours), which is comparable to that of salmeterol, hasbeen suggested to result from its association with the membranelipid bilayer, from which it gradually diffuses to provideprolonged stimulation of β2 receptors and its resistanceto MAO and COMT. Formoterol has a much faster onset ofaction than does salmeterol as result of its lower lipophilicity.Both of these long-acting drugs are used by inhalationand are recommended for maintenance treatment of asthma,usually in conjunction with an inhaled corticosteroid.
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